Predatory Game is the sixth story in Christine Feehan’s GhostWalker series. The GhostWalkers are a group of enhanced humans who have special talents, including psychic abilities and extra physical strength. They battle against the rogue creator of the GhostWalkers, Dr. Whitney, and uncover evermore complex intrigues as the series progresses.

GhostWalker Jess Calhoun is an ex-Navy SEAL who was seriously injured and is now in a wheelchair after losing the use of his legs. Dr. Lily Whitney-Russell has been carrying out some new medical treatments to help him regain the use of his legs; so far, the experiments haven't worked. Jess’s housemate of several months, Saber Wynter, appears to be hiding from an abusive husband and keeps herself to herself.

As the story begins, Saber feels that the time is approaching to move on. She's been running and hiding from Dr. Whitney, creator of the GhostWalkers, for a long time. She's just not sure that she can leave Jess, to whom she feels attracted. When they discover that they are both GhostWalkers, their newfound close friendship is sorely tested. Each finds it hard to trust the other as they could be bent on betrayal. Saber's psychic powers enable her to be a silent assassin, and her fear of Whitney and the other GhostWalkers means she wants to escape - but Jess won't let her, particularly when it becomes clear that Saber has a stalker who will stop at nothing to get at her.

Although this book refers occasionally to events in other of the GhostWalker books, it's possible to read Predatory Game without knowing the other plots and still understand what's going on. However, the complexity of the underlying plotlines of Dr. Whitney and who is good and who is bad feels rather muddled here, with Whitney seeming almost godlike in his power. Saber is a difficult character to like, mainly because she spends so much time trying to run away. I was also very unsure of her age, which makes some of the romantic elements a little uncomfortable; she tells someone that she's fourteen, she's known to change her appearance to make herself look older, and she's continually described as slender, small, tiny, etc. Jess appears to be the traditional fiction Navy SEAL type, obsessed with patriotism and honor yet also having a soft center.

This is a reasonable read, but there are some slow patches, and the coincidences or engineered sections of the plot can be difficult to take in. There were many aspects of the plot left open-ended - for example, whether the feelings between Jess and Saber are caused by the pheromones that Dr. Whitney apparently introduced. The action parts are well written and interactions between characters are good in places, but overall it isn't an entirely satisfying read.